Stefan Scheiner, Vienna University of Technology

Understanding the mechanical performance of both natural biological tissues and synthetically made biomaterials is key for making predictions as regards the probability that such materials fail under physiologically relevant loading conditions. Notably, in many cases, a distinctive hierarchical organization is observed, and the situation becomes even more intricate as the involved biological cells and factors respond, selectively, to their mechanical environment, implying that the load-bearing capacity of natural and synthetic biomaterials may evolve over time. This effect is also highly relevant when it comes to the outbreak and progression of specific pathologies, owing to the fact that mechanical loading may counteract or promote the pathological factors initiating or maintaining the respective disease.

This mini-symposium aims at bringing together experts in all related fields, in order to discuss latest insights and the grand challenges to be tackled in the near future. Considering the distinctive inter- and multidisciplinarity of the overall problems, contributions from both theoretical and experimental research are welcome in this mini-symposium, and no restriction is made as to which biological tissue is investigated. As concerns contributions dealing with theoretical modeling, multiscale approaches are particularly welcome, while uniscale approaches are considered as relevant and acceptable nonetheless.

Topics of Interest Include:

  • Multiscale modelling of biological tissues
  • Consideration of mechanobiological regulation
  • Mathematical/computational modelling
  • Experimental studies
  • Solid and fluid mechanics, mechanics of and transport in porous media